Hypertrophy
Hypertrophy is the process by which muscle fibers grow larger in cross-sectional area as an adaptation to repeated mechanical stress, primarily through resistance training. At the cellular level, the muscle fibers themselves don't multiply in significant numbers; instead, each fiber accumulates more contractile proteins (actin and myosin) and expands in diameter. The common misconception is that lifting heavier weight always produces more hypertrophy, but the actual driver is mechanical tension sustained over enough volume and time under load. Many coaches program hypertrophy work in the 6 to 20 rep range precisely because those rep counts tend to accumulate sufficient time under tension without the load being so heavy that technique breaks down after two reps. There are two subcategories worth knowing: myofibrillar hypertrophy, which increases the density of contractile proteins and yields denser, stronger muscle, and sarcoplasmic hypertrophy, which increases the fluid and glycogen content of the muscle cell, contributing more to size than raw strength. The practical upshot is that chasing hypertrophy requires progressive overload over weeks and months, enough protein to supply raw material for tissue repair, and consistent proximity to muscular failure on working sets.
Example
A lifter doing three to four sets of barbell rows in the 8 to 12 rep range, resting 90 seconds between sets, and adding small amounts of weight each week over a 12-week training block is following a textbook hypertrophy protocol. By the end of that block, the latissimus dorsi, rhomboids, and biceps have been exposed to enough cumulative tension and metabolic stress that the fibers thicken noticeably, showing up as a visibly wider back. That visible change is hypertrophy in action.